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Legume-, fish-, or high-protein-based hypocaloric diets: effects on weight loss and mitochondrial oxidation in obese men

Abete, Itziar; Parra, Dolores; Martinez, J. Alfredo

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PMID: 19298202


The nutritional composition of dietary intake could produce specific effects on metabolic variables such as mitochondrial oxidation, whose understanding could contribute to apply more individualized weight-lowering strategies. This study assessed the effects of four hypocaloric diets with high protein content or different food distribution on metabolic changes and mitochondrial oxidation accompanying weight loss. Thirty-five obese men (body mass index of 31.8 +/- 3.0 kg/m(2) and 38 +/- 7 years old) were randomly assigned to one of the four treatments (8 weeks): control diet (C-diet); legume diet (L-diet); fatty fish diet (FF-diet); or high-protein diet (HP-diet). Body composition, blood pressure, resting energy expenditure, mitochondrial oxidation, blood biomarkers, and dietary intake were assessed. The HP-diet and L-diet achieved the greater body weight reduction (-8.4 +/- 1.2% and -8.3 +/- 2.9%, respectively), as compared to the C-diet (-5.5 +/- 2.5%; P = .042). The high-density lipoprotein cholesterol concentrations were reduced in all dietary groups except for the FF-diet. Total and low-density lipoprotein cholesterol levels were significantly improved by the L-diet (P

Automatic Tags

Humans; Male; Adult; Obesity; Middle Aged; Triglycerides; Cholesterol; Body Composition; Diet, Reducing; Blood Pressure; Insulin; Blood Glucose; Oxidation-Reduction; Dietary Proteins; Mitochondria; Seafood; Fabaceae

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