Statin Use Is Associated With Diabetes Progression

A recent observational study suggests that people with diabetes who use statins experience a greater rate of diabetes progression than those who don’t use the drugs.The retrospective study of US patients in the Veterans Affairs health system included 83 022 pairs of statin users and active comparators who used a histamine-2 receptor blocker or proton pump inhibitor but not statins. The diabetes progression composite outcome included new insulin initiation, increase in the number of glucose-lowering medication classes prescribed, 5 or more blood glucose measurements of 200 mg/dL or greater, or a new diagnosis of ketoacidosis or uncontrolled diabetes.