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Body Mass Index and Risk of Stroke and Myocardial Infarction in a Relatively Lean Population
Yatsuya Hiroshi; Toyoshima Hideaki; Yamagishi Kazumasa; Tamakoshi Koji; Taguri Masataka; Harada Akiko; Ohashi Yasuo; Kita Yoshikuni; Naito Yoshihiko; Yamada Michiko; Tanabe Naohito; Iso Hiroyasu; Ueshima Hirotsugu; null null
Abstract:
Background–The association of overweight/obesity with the incidence of cardiovascular diseases, especially stroke, has not been comprehensively examined in relatively lean populations in which stroke is more prevalent than coronary heart disease.Methods and Results–Pooled individual data from 16 Japanese cohorts comprising 45 235 participants ages 40 to 89 years without previous history of cardiovascular disease were studied. During follow-up, 1113 incident strokes and 190 myocardial infarctions were identified. At baseline, mean ages of men and women were 55.4 and 56.5 years and mean body mass indices (BMI) were 23.0 and 23.4 kg/m2, respectively. Compared with those with BMI
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