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Effects of meals rich in either monounsaturated or saturated fat on lipid concentrations and on insulin secretion and action in subjects with high fasting triglyceride concentrations

Lopez, Sergio; Bermudez, Beatriz; Ortega, Almudena; Varela, Lourdes M.; Pacheco, Yolanda M.; Villar, Jose; Abia, Rocio; Muriana, Francisco J. G.

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2011-03

10.3945/ajcn.110.003251

PMID: 21209225

Abstract:

CONCLUSIONS: MUFAs postprandially buffered beta cell hyperactivity and insulin intolerance relative to SFAs in subjects with high fasting triglyceride concentrations. These data suggest that, in contrast with SFAs, MUFA-based strategies may provide cardiovascular benefits to persons at risk by limiting lipid and insulin excursions and may contribute to optimal glycemic control after meal challenges.