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Bottle of Lies: The Inside Story of the Generic Drug Boom

Publish date:
May 1, 2019
Bottle of Lies: The Inside Story of the Generic Drug Boom

Many have hailed the widespread use of generic drugs as one of the most important public-health developments of the twenty-first century. Today, almost 90 percent of our pharmaceutical market is comprised of generics, the majority of which are manufactured overseas. We have been reassured by our doctors, our pharmacists and our regulators that generic drugs are identical to their brand-name counterparts, just less expensive. But is this really true?

Katherine Eban’s Bottle of Lies exposes the deceit behind generic-drug manufacturing—and the attendant risks for global health. Drawing on exclusive accounts from whistleblowers and regulators, as well as thousands of pages of confidential FDA documents, Eban reveals an industry where fraud is rampant, companies routinely falsify data, and executives circumvent almost every principle of safe manufacturing to minimize cost and maximize profit, confident in their ability to fool inspectors. Meanwhile, patients unwittingly consume medicine with unpredictable and dangerous effects.

The story of generic drugs is truly global. It connects middle America to China, India, sub-Saharan Africa and Brazil, and represents the ultimate litmus test of globalization: what are the risks of moving drug manufacturing offshore, and are they worth the savings?

A decade-long investigation with international sweep, high-stakes brinkmanship and big money at its core, Bottle of Lies reveals how the world’s greatest public-health innovation has become one of its most astonishing swindles.

I loved this book and it is disturbingly similar to the nutrition field. 

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Generic Drugs
Generic drugs are medications that are identical or bioequivalent to brand-name drugs in terms of dosage form, safety, strength, route of administration, quality, and intended use. They contain the same active ingredients as the brand-name drugs and are typically sold at a lower price. When a pharmaceutical company develops a new drug, it is granted a patent that gives them exclusive rights to manufacture and sell the drug for a certain period, typically 20 years. After the patent expires, other manufacturers can produce generic versions of the drug, provided they meet the regulatory requirements set by the health authorities.
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