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Historical Event

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January 1, 1954

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Keys confidently declares that fat in the diet leads to serum cholesterol and thus heart disease.

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"No other variable in the mode of life besides the fat calories in the diet is known which shows anything like such a consistent relationship to the mortality rate from coronary or degenerative heart disease," he[Ancel Keys] told his colleagues at a gathering to discuss artheroschlerosis in 1954.

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Big Fat Surprise -page 27

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Diet-Heart Hypothesis
The diet-heart hypothesis, also known as the lipid hypothesis, proposes that there is a direct relationship between dietary fat intake, particularly saturated fat and cholesterol, and the development of heart disease. It suggests that consuming high amounts of these fats leads to an increase in blood cholesterol levels, specifically low-density lipoprotein (LDL) cholesterol, which in turn contributes to the formation of atherosclerotic plaques in the arteries. Some consider this hypothesis nothing more than wishful thinking.
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