Historical Event
Date:
August 24, 1957
Short Description:
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Keys reinforces his diet-heart hypothesis with a new paper.
Title:
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DIET AND THE EPIDEMIOLOGY OF CORONARY HEART DISEASE
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Important Text:
August 24, 1957
DIET AND THE EPIDEMIOLOGY OF CORONARY HEART DISEASE
Author Affiliations
JAMA. 1957;164(17):1912-1919. doi:10.1001/jama.1957.62980170024007e
FullText
Abstract
Researches ranging from laboratory experiments to epidemiology on a world-wide basis have led to the hypothesis that the fat content of the habitual diets of populations has an important effect on the frequency of coronary heart disease in those populations. The general nature and some of the evidence for this hypothesis have been summarized several times in recent years,1 but progress in this field manages to outdate each new résumé by the time it reaches print. Not that the previously cited facts or the hypothesis itself have been found to be erroneous; on the contrary, each new research adds detail, reduces areas of uncertainty, and, so far, provides further reason to believe that along the line of this hypothesis we may hope to find effective measures to reduce the incidence of coronary heart disease.
Topics: (click image to open)
Heart Disease | Heart disease, also known as cardiovascular disease, refers to a range of conditions that affect the heart and blood vessels. It is a broad term that encompasses various conditions, including coronary artery disease, heart failure, arrhythmias, and valvular heart diseases, among others. Heart disease is a leading cause of death worldwide. | |
Diet-Heart Hypothesis | The diet-heart hypothesis, also known as the lipid hypothesis, proposes that there is a direct relationship between dietary fat intake, particularly saturated fat and cholesterol, and the development of heart disease. It suggests that consuming high amounts of these fats leads to an increase in blood cholesterol levels, specifically low-density lipoprotein (LDL) cholesterol, which in turn contributes to the formation of atherosclerotic plaques in the arteries. Some consider this hypothesis nothing more than wishful thinking. |