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Influence of feeding on metabolite excretion evidenced by urine 1H NMR spectral profiles: a comparison between subjects living in Rome and subjects living at arctic latitudes (Svaldbard)

Zuppi, C.; Messana, I.; Forni, F.; Ferrari, F.; Rossi, C.; Giardina, B.

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PMID: 9877127


Urines from 25 normal subjects living in Rome and 25 normal subjects living in Ny-Alesund (Svaldbard) were analysed by 1HNMR spectroscopy. The observed differences in the concentration of the major metabolites were correlated to the composition of the diet. It was found that a diet rich of carbohydrates, such as the Italian diet, is responsible for an increased excretion of citrate, lactate, alanine, and glycine. Thus, a correct diagnostical interpretation of urinary metabolites needs to consider feeding habits.

Automatic Tags

Female; Humans; Male; Adult; Middle Aged; Magnetic Resonance Spectroscopy; Reference Values; Dietary Carbohydrates; Lactic Acid; Arctic Regions; Amino Acids; Methylamines; Protons; Dimethylamines; Citric Acid; Hippurates; Rome

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