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Metabolomics-Based Analysis of Banana and Pear Ingestion on Exercise Performance and Recovery

Nieman, David C.; Gillitt, Nicholas D.; Sha, Wei; Meaney, Mary Pat; John, Casey; Pappan, Kirk L.; Kinchen, Jason M.

Date Published:





Extra Links:

December 4, 2015


PMID: 26561314


Bananas and pears vary in sugar and phenolic profiles, and metabolomics was utilized to measure their influence on exercise performance and recovery. Male athletes (N = 20) cycled for 75 km while consuming water (WATER), bananas (BAN), or pears (PEAR) (0.6 g carbohydrate/kg each hour) in randomized order. UPLC-MS/MS and the library of purified standards maintained by Metabolon (Durham, NC) were used to analyze metabolite shifts in pre- and postexercise (0-h, 1.5-h, 21-h) blood samples. Performance times were 5.0% and 3.3% faster during BAN and PEAR versus WATER (P = 0.018 and P = 0.091, respectively), with reductions in cortisol, IL-10, and total leukocytes, and increases in blood glucose, insulin, and FRAP. Partial Least Square Discriminant Analysis (PLS-DA) showed a distinct separation between trials immediately (R(2)Y = 0.877, Q(2)Y = 0.457) and 1.5-h postexercise (R(2)Y = 0.773, Q(2)Y = 0.441). A total of 107 metabolites (primarily lipid-related) increased more than 2-fold during WATER, with a 48% and 52% reduction in magnitude during BAN and PEAR recovery (P

Automatic Tags

Humans; Male; Adult; Middle Aged; Exercise; Diet; Dietary Carbohydrates; Insulin; Blood Glucose; oxidative stress; carbohydrate; Exercise Test; Hydrocortisone; Lactic Acid; Antioxidants; Metabolomics; polyphenols; Cytokines; Phenols; Metabolome; Blood Cell Count; cycling; Musa; Pyrus

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