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Repeated Amblyomma testudinarium tick bites are associated with increased galactose-alpha-1,3-galactose carbohydrate IgE antibody levels: A retrospective cohort study in a single institution

Hashizume, Hideo; Fujiyama, Toshiharu; Umayahara, Takatsune; Kageyama, Reiko; Walls, Andrew F.; Satoh, Takahiro

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2018-06

10/gdmfbs

PMID: 29273488

Abstract:

CONCLUSION: In Amblyomma tick bite lesions, basophils; eosinophils; and type 2, cytokine-producing T cells infiltrate the skin and alpha-gal IgE antibodies are produced. These findings provide a potential mechanistic connection between Amblyomma bites and red meat hypersensitivity. Copyright © 2017 American Academy of Dermatology, Inc. Published by Elsevier Inc. All rights reserved.

Automatic Tags

alpha-gal syndrome; basophil; eosinophil; interferon gamma; interleukin 4; tick bite; type 2 T cell