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Innovation: Metabolomics: the apogee of the omics trilogy

Patti, Gary J.; Yanes, Oscar; Siuzdak, Gary

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March 22, 2012

10/ggc5jg

PMID: 22436749 PMCID: PMC3682684

Abstract:

Metabolites, the chemical entities that are transformed during metabolism, provide a functional readout of cellular biochemistry. With emerging technologies in mass spectrometry, thousands of metabolites can now be quantitatively measured from minimal amounts of biological material, which has thereby enabled systems-level analyses. By performing global metabolite profiling, also known as untargeted metabolomics, new discoveries linking cellular pathways to biological mechanism are being revealed and are shaping our understanding of cell biology, physiology and medicine.

Automatic Tags

Metabolomics; Mass Spectrometry; Biochemical Phenomena

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