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Interleukin-10

de Waal Malefyt, René; Hans, Yssel; Roncarolo, Maria-Grazia; Spits, Hergen; de Vries, Jan E.

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May 31, 1992

10.1016/0952-7915(92)90082-P

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Abstract:

Despite the short history of interleukin-10, accumulated evidence indicates that this interleukin plays a major role in suppressing immune and inflammatory responses. Yet interleukin-10 also maintains cell viability and acts as a cofactor to promote the growth of lymphoid and myleloid cells in vitro. Here we review the present knowledge on the structure and function of interleukin-10.