< Back

SGLT2 Inhibition Mediates Protection from Diabetic Kidney Disease by Promoting Ketone Body-Induced mTORC1 Inhibition

Tomita, Issei; Kume, Shinji; Sugahara, Sho; Osawa, Norihisa; Yamahara, Kosuke; Yasuda-Yamahara, Mako; Takeda, Naoko; Chin-Kanasaki, Masami; Kaneko, Tatsuroh; Mayoux, Eric; Mark, Michael; Yanagita, Motoko; Ogita, Hisakazu; Araki, Shin-ichi; Maegawa, Hiroshi

Date Published:

Publication:

DOI:

URL:

PMID:

Extra Links:

July 28, 2020

10.1016/j.cmet.2020.06.020

Click to open url

Publisher: Elsevier PMID: 32726607

Extra Link

Abstract:

Automatic Tags

atherosclerosis; ketolysis; ketone body; diabetic kidney disease; mTORC1; lipolysis; nutrient-sensing signal; renal energy metabolism; SGLT2 inhibitor