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Dietary-regulation of catabolic disposal of 4-hydroxynonenal analogs in rat liver

Li, Qingling; Tomcik, Kristyen; Zhang, Shenghui; Puchowicz, Michelle A.; Zhang, Guo-Fang

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March 15, 2012

10.1016/j.freeradbiomed.2011.12.022

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Publisher: NIH Public Access PMID: 22245097

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Abstract:

Our previous work in perfused rat livers has demonstrated that 4-hydroxynonenal (HNE) is catabolized predominantly via beta oxidation. Therefore, we hypothesized that perturbations of beta oxidation, such as diet-altered fatty acid oxidation activity, ...