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Treatment of familial male-limited precocious puberty with bicalutamide and anastrozole

Kreher, Nerissa C; Pescovitz, Ora Hirsch; Delameter, Paul; Tiulpakov, Anatoly; Hochberg, Ze'ev

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2006-09

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10.1016/j.jpeds.2006.04.027

PMID: 16939760

Abstract:

This report describes the use of bicalutamide and anastrozole in two subjects with familial male-limited precocious puberty. Clinical improvements include decreased facial acne and pubic hair. Most importantly, a marked decrease in growth velocity and skeletal advancement has been achieved.

Automatic Tags

Humans; Male; Child; Child, Preschool; Mutation; Puberty, Precocious; Androgen Antagonists; Anilides; Aromatase Inhibitors; Nitriles; Receptors, LH; Tosyl Compounds; Triazoles

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