The Association Between Lower Levels of Low-Density Lipoprotein Cholesterol and Cancer Predates the Diagnosis of Cancer by 18 Years

We recently reported, in a meta-analysis of statin trials, a strong association between low concentrations of low-density lipoprotein cholesterol (LDL-C) and incident cancer risk. Interpretation of these data has been a point of significant debate. At issue is whether low LDL-C concentration