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Country-wide medical records infer increased allergy risk of gastric acid inhibition

Jordakieva, Galateja; Kundi, Michael; Untersmayr, Eva; Pali-Schöll, Isabella; Reichardt, Berthold; Jensen-Jarolim, Erika

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July 30, 2019

10.1038/s41467-019-10914-6

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Number: 1 Publisher: Nature Publishing Group

Abstract:

Gastric acid inhibitors promote experimental allergy in animals, and have been linked to allergy risk in observational human studies. Here the authors show in a country-wide medical record analysis that allergy development risk is doubled in gastric acid inhibitor users, and is higher in women and in older age.