Metformin decreases angiogenesis via NF-κB and Erk1/2/Erk5 pathways by increasing the antiangiogenic thrombospondin-1

Tan, Bee K.; Adya, Raghu; Chen, Jing; Farhatullah, Syed; Heutling, Dennis; Mitchell, Dan; Lehnert, Hendrik; Randeva, Harpal S.