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Transient structure and dynamics in the disordered c-Myc transactivation domain affect Bin1 binding

Andresen, Cecilia; Helander, Sara; Lemak, Alexander; Farès, Christophe; Csizmok, Veronika; Carlsson, Jonas; Penn, Linda Z.; Forman-Kay, Julie D.; Arrowsmith, Cheryl H.; Lundström, Patrik; Sunnerhagen, Maria

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June 30, 2012

10.1093/nar/gks263

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Abstract:

Abstract. The crucial role of Myc as an oncoprotein and as a key regulator of cell growth makes it essential to understand the molecular basis of Myc function.