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Uric acid and evolution

Álvarez-Lario, Bonifacio; Macarrón-Vicente, Jesús

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October 31, 2010

10.1093/rheumatology/keq204

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Publisher: Oxford Academic

Abstract:

Abstract. Uric acid (UA) is the end product of purine metabolism in humans due to the loss of uricase activity by various mutations of its gene during the Mioc