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Induction of Colon Cancer in Mice with 1,2-Dimethylhydrazine

Gurley, Kay E.; Moser, Russell D.; Kemp, Christopher J.

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August 31, 2015

10.1101/pdb.prot077453

PMID: 26330619

Abstract:

In this protocol, colon cancer is induced in mice through a series of injections with 1,2-dimethylhydrazine. Mice will develop primarily colon tumors starting at about 3 mo after the first injection. Tumors in the lung, uterus, and small intestine may also be seen, as well as lymphomas.

Automatic Tags

Time Factors; Mice; Colonic Neoplasms; Injections, Subcutaneous; 1,2-Dimethylhydrazine

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