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Medicines and Vegetable Oils as Hidden Causes of Cardiovascular Disease and Diabetes. [Review]

Okuyama, Harumi; Langsjoen, Peter H.; Ohara, Naoki; Hashimoto, Yoko; Hamazaki, Tomohito; Yoshida, Satoshi; Kobayashi, Tetsuyuki; Langsjoen, Alena M.

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2016

10.1159/000446704

PMID: 27251151

Abstract:

KEY MESSAGES: To date, no randomized controlled trials (RCTs) have been performed to prove the above interpretation. However, the opposite types of RCT trials have been performed by increasing the intake of high-linoleic vegetable oils and reducing that of animal fats, which resulted in increased CVD and all-cause mortality. The amounts of these vegetable oils to exhibit adverse effects in animal studies are not huge (