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ECG changes during haloperidol and pimozide treatment of Tourette's disorder

Fulop, G.; Phillips, R. A.; Shapiro, A. K.; Gomes, J. A.; Shapiro, E.; Nordlie, J. W.

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1987-05

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10.1176/ajp.144.5.673

PMID: 3555126

Abstract:

The ECG QTc interval was significantly prolonged by pimozide but not haloperidol or placebo in a randomized clinical trial with 40 patients with Tourette's disorder. However, no adverse cardiac effects or differences in rate, rhythm, or waveform were found.

Automatic Tags

Female; Humans; Male; Adult; Random Allocation; Heart Rate; Heart; Clinical Trials as Topic; Electrocardiography; Placebos; Haloperidol; Pimozide; Tourette Syndrome

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