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Impact of the Swank and Wahls elimination dietary interventions on fatigue and quality of life in relapsing-remitting multiple sclerosis: The WAVES randomized parallel-arm clinical trial

Wahls, Terry L; Titcomb, Tyler J; Bisht, Babita; Eyck, Patrick Ten; Rubenstein, Linda M; Carr, Lucas J; Darling, Warren G; Hoth, Karin F; Kamholz, John; Snetselaar, Linda G

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July 1, 2021

10.1177/20552173211035399

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Publisher: SAGE Publications Ltd

Abstract:

ObjectiveTo compare the effect of the modified Paleolithic elimination (Wahls) and low-saturated fat (Swank) diets in relapsing-remitting MS (RRMS).MethodsIndividuals (n?=?87) with RRMS were randomized to the Swank or Wahls diets in a parallel group clinical trial consisting of four timepoints: 1) run-in, 2) baseline, 3) 12-weeks, and 4) 24-weeks.Results77 participants completed 12?weeks and 72 completed 24?weeks. The 12-week change from baseline in fatigue was -0.94?±?0.18 (FSS) and -9.87?±?1.93 (MFIS; both p?

Automatic Tags

paleolithic diet; quality of life; fatigue; Multiple sclerosis; 6-minute walk test; low-saturated fat diet