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Ketogenic diet in epileptic children: impact on lipoproteins and oxidative stress. [Review]

Lima, Patricia Azevedo; de Brito Sampaio, Leticia Pereira; Damasceno, Nagila Raquel Teixeira

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2015

10.1179/1476830515Y.0000000036

PMID: 26177187

Abstract:

DISCUSSION: The positive effects of KD on the health of children and adolescents with refractory epilepsy are unquestionable. Conversely, this positive role is associated with significant and negative changes in lipid metabolism. Moreover, the positive effects are possibly related to oxidative reactions and unbalance of antioxidants that can contribute to an increased cardiometabolic risk. Therefore, this review invites clinicians and researchers to investigate the lipid and oxidative metabolism in their clinical practice and trials, respectively.

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