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Effects of weight loss during a very low carbohydrate diet on specific adipose tissue depots and insulin sensitivity in older adults with obesity: a randomized clinical trial

Goss, Amy M.; Gower, Barbara; Soleymani, Taraneh; Stewart, Mariah; Pendergrass, May; Lockhart, Mark; Krantz, Olivia; Dowla, Shima; Bush, Nikki; Garr Barry, Valene; Fontaine, Kevin R.

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August 12, 2020

10.1186/s12986-020-00481-9

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Abstract:

Insulin resistance and accumulation of visceral adipose tissue (VAT) and intermuscular adipose tissue (IMAT) place aging adults with obesity at high risk of cardio-metabolic disease. A very low carbohydrate diet (VLCD) may be a means of promoting fat loss from the visceral cavity and skeletal muscle, without compromising lean mass, and improve insulin sensitivity in aging adults with obesity.