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Ketogenic diet for mitochondrial disease: a systematic review on efficacy and safety

Zweers, Heidi; Wegberg, Annemiek M. J. van; Janssen, Mirian C. H.; Wortmann, Saskia B.

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2021

10.1186/s13023-021-01927-w

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Publisher: BioMed Central PMID: 34217336

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Abstract:

No curative therapy for mitochondrial disease (MD) exists, prioritizing supportive treatment for symptom relief. In animal and cell models ketones decrease oxidative stress, increase antioxidants and scavenge free radicals, putting ketogenic diets (KDs) ...