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Efficacy of the Atkins diet as therapy for intractable epilepsy

Kossoff, Eric H.; Krauss, Gregory L.; McGrogan, Jane R.; Freeman, John M.

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December 22, 2003

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10.1212/01.wnl.0000098889.35155.72

PMID: 14694049

Abstract:

The ketogenic diet is effective for treating seizures in children with epilepsy. The Atkins diet can also induce a ketotic state, but has fewer protein and caloric restrictions, and has been used safely by millions of people worldwide for weight reduction. Six patients, aged 7 to 52 years, were started on the Atkins diet for the treatment of intractable focal and multifocal epilepsy. Five patients maintained moderate to large ketosis for periods of 6 weeks to 24 months; three patients had seizure reduction and were able to reduce antiepileptic medications. This provides preliminary evidence that the Atkins diet may have a role as therapy for patients with medically resistant epilepsy.

Automatic Tags

Female; Humans; Male; Adolescent; Adult; Epilepsy; Child; Middle Aged; Diet; Dietary Carbohydrates; Lipids; Ketosis; Treatment Outcome; Body Weight; Remission Induction; Electroencephalography; Seizures; Anticonvulsants; Drug Resistance

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