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Large-scale identification of extracellular plant miRNAs in mammals implicates their dietary intake

Chen, Xi; Liu, Lu; Chu, Qinjie; Sun, Shuo; Wu, Yixuan; Tong, Zhou; Fang, Weijia; Timko, Michael P.; Fan, Longjiang

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2021

10.1371/journal.pone.0257878

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Publisher: Public Library of Science PMID: 34587184

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Abstract:

Extracellular microRNAs (miRNAs) have been proposed to function in cross-kingdom gene regulation. Among these, plant-derived miRNAs of dietary origin have been reported to survive the harsh conditions of the human digestive system, enter the circulatory ...