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Iron Concentration in Deep Gray Matter Structures is Associated with Worse Visual Memory Performance in Healthy Young Adults
Gergely, Darnai; Nagy, Szilvia; Horvath, Reka; Acs, Peter; Perlaki, Gabor; Orsi, Gergely; Kovács, Norbert; Altbacker, Anna; Plózer, Enikő; Tényi, Dalma; Weintraut, Rita; Schwarcz, Attila; John, Flora; Varga, Eszter; Bereczkei, Tamás; Clemens, Zsofia; Komoly, Samuel; Janszky, József
Abstract:
Abnormally high deposition of iron can contribute to neurodegenerative disorders with cognitive impairment. Since previous studies investigating cognition-brain iron accumulation relationships focused on elderly people, our aim was to explore the association between iron concentration in subcortical nuclei and two types of memory performances in a healthy young population. Gender difference was found only in the globus pallidus. Our results showed that iron load characterized by R2* value on the MRI in the caudate and putamen was related to visual memory, while verbal memory was unrelated to iron concentration.
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