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Effects of 8-hour time restricted feeding on body weight and metabolic disease risk factors in obese adults: A pilot study

Gabel, Kelsey; Hoddy, Kristin K.; Haggerty, Nicole; Song, Jeehee; Kroeger, Cynthia M.; Trepanowski, John F.; Panda, Satchidananda; Varady, Krista A.

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10.3233/NHA-170036

PMID: 29951594 PMCID: PMC6004924

Abstract:

BACKGROUND: Time restricted feeding decreases energy intake without calorie counting and may be a viable option for weight loss. However, the effect of this diet on body weight in obese subjects has never been examined. OBJECTIVE: This study investigated the effects of 8-h time restricted feeding on body weight and metabolic disease risk factors in obese adults. DESIGN: Obese subjects (n = 23) participated in an 8-h time restricted feeding intervention (ad libitum feeding between 10:00 to 18:00 h, water fasting between 18:00 to 10:00 h) for 12 weeks. Weight loss and other outcomes were compared to a matched historical control group (n = 23). RESULTS: Body weight and energy intake decreased in the time restricted group (–2.6% ± 0.5; –341 ± 53 kcal/d) relative to controls over 12 weeks (P < 0.05). Systolic blood pressure decreased in the time restricted feeding group (–7 ± 2 mm Hg) versus controls (P 

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