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Dietary fat intake and risk of cardiovascular disease and all-cause mortality in a population at high risk of cardiovascular disease

Guasch-Ferre, Marta; Babio, Nancy; Martinez-Gonzalez, Miguel A.; Corella, Dolores; Ros, Emilio; Martin-Pelaez, Sandra; Estruch, Ramon; Aros, Fernando; Gomez-Gracia, Enrique; Fiol, Miquel; Santos-Lozano, Jose M.; Serra-Majem, Lluis; Bullo, Monica; Toledo, Estefania; Barragan, Rocio; Fito, Montserrat; Gea, Alfredo; Salas-Salvado, Jordi; Investigators, PREDIMED Study

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2015-12

10.3945/ajcn.115.116046

PMID: 26561617

Abstract:

CONCLUSIONS: Intakes of MUFAs and PUFAs were associated with a lower risk of CVD and death, whereas SFA and trans-fat intakes were associated with a higher risk of CVD. The replacement of SFAs with MUFAs and PUFAs or of trans fat with MUFAs was inversely associated with CVD. This trial was registered at www.controlled-trials.com as ISRCTN 35739639. Copyright © 2015 American Society for Nutrition.