Recent History
July 15, 1852
Jean-Francois Dancel
Obesity, Carnivore, Keto
Obesity, or, Excessive corpulence : the various causes and the rational means of cure
An English lady from Dieppe wrote of the meat-obesity cure "I at once made trial of your plan for the cure of obesity, and have already experienced considerable improvement."
An English lady wrote to me from Dieppe, on the 15th of July, 1852. The following is an extract from her letter:—"Arrived here only a short time ago. I at once made trial of your plan for the cure of obesity, and have already experienced considerable improvement. I have not yet had an opportunity of being weighed, and therefore cannot assert positively that my actual weight is less than it was, but I certainly feel lighter, and my hands are neither so red nor so fat as formerly."
August 7, 1852
Jean-Francois Dancel
Obesity, Carnivore, Keto
Obesity, or, Excessive corpulence: the various causes and the rational means of cure
M. Alcide Desbouillons uses Dr Dancel's carnivore diet advice to win his battle with corpulency.
On the 7th August, 1852, M. Alcide Desbouillons wrote to me from Brest, to the effect that his corpulence was a source of great inconvenience; that his duties required him to be much on horseback, and consequently in hot weather he suffered greatly from fatigue. He weighed two hundred pounds, and measured forty-nine inches in circumference. On the 2nd September, after twenty days' trial of my system, and, as he says, perhaps not as rigorously carried out as it should have been, he weighed himself again, and obtained the following result: Weight, one hundred and eighty-nine pounds: circumference, forty-five inches. Twenty days after this he weighed one hundred and eighty-seven pounds, and measured forty-three inches in circumference. This was but a slight difference; yet M. Desbouillons, after the first few days of treatment, could walk with less difficulty, was more active, and was no longer bathed in perspiration. In his last letter he says, "I am continuing your plan of treatment, and expect to find a notable amelioration both in size and weight. The effects produced by your medicine have been in perfect accord with what you had led me to expect. The experiment appears so far conclusive, and I trust that my case will prove thoroughly demonstrative."
January 1, 1853
Jean-Francois Dancel
Obesity, Carnivore, Keto
Obesity, or, Excessive corpulence : the various causes and the rational means of cure
Dancel writes "On the publication of the first edition of my treatise upon Obesity, I experienced a degree of impatience, and even irritation, in view of the systematic opposition which a self-evident truth received at the hands of the medical profession. At the present time, however, I calmly recognize that the same happened in the case of every attempted innovation."
If free from prejudice, and willing to acknowledge the truth of that which is manifest, the cases we have just cited ought to satisfy any candid enquirer that obesity may be entirely overcome without prejudicially affecting the general health. At first sight, this would appear undeniable; yet medical writers, who have hitherto insisted that a meat diet is conducive to the development of fat, and that vegetables have an opposite tendency, will not frankly acknowledge their error.
Physicians who have derived their knowledge from books, and from the lectures of their teachers, must find it difficult to change their opinions in reference to obesity. With the public, when any one is told that the imbibition of large quantities of water is productive of fat, and that feeding upon animal food induces leanness, a similar degree of doubt is excited as when Galileo asserted that the sun did not revolve around the earth. On the publication of the first edition of my treatise upon Obesity, I experienced a degree of impatience, and even irritation, in view of the systematic opposition which a self-evident truth received at the hands of the medical profession. At the present time, however, I calmly recognize that the same happened in the case of every attempted innovation. I call to mind how Galileo endangered his very existence. Vesalius, the founder of anatomy, was saved from the stake only by the interference of his sovereign. Harvey, the discoverer of the circulation, was compelled to seek royal protection from the attacks of the medical men of his day. Peysonnel, a physician of Marseilles, and a great naturalist, devoted himself to the study of corals and madrepores. In 1727, he laid before the Academy of Science a monogram, proving to demonstration that corals and madrepores are structures due to animal life; that what Dioscorides, Pliny, Linnæus, Lamarck, Tournefort, &c. &c. had thought to be flowers, are in truth animals; and that these living creatures constructed and augmented their abodes; the Academy, like most learned bodies, admitted as truth only that which it taught, and consequently paid no attention to this memoir, which, nevertheless, was destined to produce an entire change in a large department of natural history. When, long afterwards, Trembley published his discoveries on fresh-water polypes, the studies of Dr. Peysonnel in this direction were remembered, and naturalists were forced to admit that the physician of Marseilles was right in maintaining that what had been taken for flowers are in reality animals. His claim as the discoverer of a fact which was destined to effect an important revolution in an extensive department of natural history, has since then not been disputed, nor could it be. All men, and men of science especially, require time before yielding to evidence, when that evidence is in opposition to preconceived views, and interferes with personal interest.
The system I have introduced progresses, and, as some might say, works wonders, and effects cures in France, in England, in Belgium, in Austria, in Russia, in Turkey, in Africa; and in almost every instance, my patients are persons occupying prominent positions—magistrates, state authorities, general officers, or men of wealth, who have enjoyed the advantages of a good education, and are able to judge of and appreciate the merits of my mode of treatment. The judgment of such a tribunal should convince the incredulous. This is no matter of faith. I lay claim to the possession of no revelation, which is not to be explained, or which is to rest solely upon my assertion. I do not say that my discovery is a mystery, and that it is your part to believe in it. Under such circumstances, disbelief would not astonish me, notwithstanding all the cases of cure brought forward; but when the nutrition of the body is explained in accordance with the laws of nature, when it is shewn to be in conformity with the well understood laws of chemistry, and that facts are cited, in reference both to man and the lower animals, in support of these phenomena, I confess that opposition to this system excites my astonishment. Physicians cannot by any possibility advance sufficient reasons against a system which, when once explained, must appear self-evident to every one.
Another fact in support of this system must be submitted to my readers. What would a medical man say if I should venture the following piece of advice: You have a horse you wish to dispose of. He is a good beast, and travels well, but he is thin. If he were fatter, he would look better, and you could sell him to greater advantage. Make him fat; and if, in order to do this, I advised him to give his horse a double allowance of oats, he would only laugh at me. He would say; why, everybody knows that if you wish to fatten a horse, the best way is to give him, in addition to an abundance of hay, bran, mixed with plenty of water, or in other words, bran mashes; or the horse may be sent to pasture, to live upon grass, which is composed principally of water and a small proportion of ligneous matter. Under such circumstances, the horse will make fat, and his form will become more round and plump; but if, when he was thin, he was able to travel thirty miles without sweating and without fatigue, now that he is fat he will scarcely be able to go five without being covered with sweat, and without shewing manifest signs of fatigue. When thin, he was a good horse; but being fat, he has lost his best qualities, which can be restored only by feeding him again upon less bulky food, with a due allowance of oats, and a small proportion of water.
I have been informed that the gentleman in charge of the stud of King Charles X. availed himself of the knowledge of this fact, and allowed only half the usual quantity of water to the horses under his charge, and that this plan was attended with the most satisfactory results, the horses being thereby able to endure a greater amount of fatigue than under a full allowance of water.
February 18, 1853
Jean-Francois Dancel
Obesity, Carnivore, Keto
Obesity, or, Excessive corpulence : the various causes and the rational means of cure
Mr L reports success - "I experienced considerable benefit—in fact I lost nine pounds in weight, and felt more active and much more fit for business."
On the 18th of February, 1853, I received a letter from Mr. L., superintendent of a royal factory at Annecy, in Savoy, in which he says: "You were kind enough to send on the 20th of April, 1851, medicine sufficient for two months of anti-obesic treatment. Your directions were scrupulously attended to during the first month, and I experienced considerable benefit—in fact I lost nine pounds in weight, and felt more active and much more fit for business. Circumstances prevented my continuing the treatment during the second month and the medicine has been lost. After the lapse of two years I am anxious to resume your plan of treatment, &c." It is now a year since Mr. L. wrote to me, when I sent him all that was requisite. I have not since heard from him by letter, but I know that the second treatment was equally satisfactory. Owing to his favorable report of my system, a notary of Annecy, during the course of last summer, sought my advice. I am also indebted to him for other patients.
June 8, 1853
Jean-Francois Dancel
Obesity, Carnivore, Keto
Obesity, or, Excessive corpulence: the various causes and the rational means of cure
On the 8th of June Dr. Halberg wrote: "I find myself infinitely better, my breathing is easy, and I am considerably reduced in size."
"Nismes (Gard) 4th Aug., 1853.
"Sir,—I have read with much interest the second edition of your precepts, based upon chemistry, for the diminution of obesity, and have carefully examined every statement you have so clearly set forth. The result is, that I am anxious to follow your advice, and to place myself under your course of treatment. I am a doctor of philosophy and professor in the Imperial Lyceum at Nismes. During my whole life I have struggled against this terrible obesity, but almost always in vain. Nevertheless I have succeeded upon two occasions: the first, about twenty years ago, by travelling on foot for three months among the forests and mountains of the north of Europe; the second time, about twelve years ago, by dint of continued and intense intellectual labour. Owing to the sedentary nature of my duties, obesity has since returned in a more threatening manner, and is no doubt the exciting cause of many ailments to which I am now subject, such as accumulation of mucus in the air passages, giving rise to cough, more especially troublesome because I am obliged to talk during the greater part of the day; cold feet, with swelling of the legs and ankles, &c., so that I am no longer able to perform the duties upon which my daily bread depends. My medical attendant can do nothing for me. He has prescribed purgatives and a vegetable diet, without any good result. I have taken thousands of Morrison's pills, and am worse rather than better, and now my mind is made up to make a trial of your plan of treatment, in full confidence that a cure may yet be accomplished.
"Doctor Halberg,
"Professor at the Imperial Lyceum of Nismes."
On the 8th of June Dr. Halberg wrote:
"I find myself infinitely better, my breathing is easy, and I am considerably reduced in size. My great desire is that the swelling in my legs may wholly disappear.
"Dr. Halberg."
Ancient History
Luxor, Luxor Governorate, Egypt
2475
B.C.E.
The Earliest Record of Sudden Death Possibly Due to Atherosclerotic Coronary Occlusion
WALTER L. BRUETSCH
The sudden death of an Egyptian noble man is portrayed in the relief of a tomb from the Sixth Dynasty (2625-2475 B.C.). Since there is indisputable evidence from the dissections of Egyptian mummies that atherosclerosis was prevalent in ancient Egypt, it was conjectured that the sudden death might have been due to atherosclerotic occlusion of the coronary arteries.
It may be presumptuous to assume that an Egyptian relief sculpture from the tomb of a noble of the Sixth Dynasty (2625-2475 B.C.) may suggest sudden death possibly due
to coronary atherosclerosis and occlusion. Much of the daily life of the ancient Egyptians has been disclosed to us through well-preserved tomb reliefs. In the same tomb that contains the scene of the dying noble, there is the more widely known relief "Netting Wildfowl in the Marshes." The latter sculpture reveals some of the devices used four thousand years ago for catching waterbirds alive. It gives a minute account of this occupation, which in ancient Egypt was both a sport and a means of livelihood for the professional hunter.
The relief (fig. 1), entitled "Sudden Death," by the Egyptologist von Bissing2 represents a nobleman collapsing in the presence of his servants. The revelant part of the explanatory text, as given by von Bissing, follows (translation by the author):
The interpretation of the details of the theme is left to the observer. We must attempt to comprehend the intentions of the ancient artist who sculptured this unusual scene. In the upper half (to the right) are two men with the customary brief apron, short hair covering the ears, busying themselves with a third man, who obviously has collapsed. One of them, bending over him, has grasped with both hands the left arm of the fallen man; the other servant, bent in his left knee, tries to uphold him by elevating the head and neck, using the knee as a support. Alas, all is in vain. The movement of the left hand of this figure, beat- ing against the forehead, seems to express the despair; and also in the tightly shut lips one can possibly recognize a distressed expression. The body of the fallen noble is limp. . . . Despite great restraint in the interpretation, the impression which the artist tried to convey is quite obvious. The grief and despair are also expressed by the figures to the left. The first has put his left hand to his forehead. (This gesture represents the Egyptian way of expressing sorrow.) At the same time he grasps with the other arm his companion who covers his face with both hands. The third, more impulsively, unites both hands over his head. ... The lord of the tomb, Sesi, whom we can identify here, has suddenly collapsed, causing consternation among his household.
In the section below (to the left) is shown the wife who, struck by terror, has fainted and sunk totheflor. Two women attendants are seen giving her first aid. To the right, one observes the wife, holding on to two distressed servants, leaving the scene. . . .
von Bissing mentions that the artist of the relief must have been a keen observer of real life. This ancient Egyptian scene is not unlike the tragedy that one encounters in present days, when someone drops dead of a "heart attack." The physician of today has almost no other choice than to certify the cause of such a death as due to coronary occlusion or thrombosis, unless the patient was known tohave been aflictedwith rheumatic heart disease or with any of the other more rare conditions which may result in sudden death.
Atherosclerosis among the Ancient Egyptians
The most frequent disease of the coronary arteries, causing sudden death, is atherosclerosis. What evidence is available that atherosclerosis was prevalent in ancient Egypt?
The first occasion to study his condition in peoples of ancient civilizations presented itself when the mummified body of Menephtah (approx.1280-1211B.C.), the reported "Pharaoh of the Hebrew Exodus" from Egypt was found. King Menephtah had severe atherosclerosis. The mummy was unwrapped by the archaeologist Dr. G. Elliot Smith, who sent a piece of the Pharaoh's aorta to Dr. S. G. Shattock of London (1908). Dr. Shattock was able to prepare satisfactory microscopic sections which revealed advanced aortic atherosclerosis with extensive depositions of calcium phosphate.
This marked the beginning of the important study of arteriosclerosis in Egyptian mummies by Sir Mare Armand Ruffer, of the Cairo Medical School(1910-11). His material included mummies ranging over a period of about 2,000 years (1580 B.C. - 525 A.D.).
The technic of embalming in the days of ancient Egypt consisted of the removal of all the viscera and of most of the muscles, destroying much of the arterial system. Often, however, a part or at times the whole aorta or one of the large peripheral arteries was left behind. The peroneal artery, owing to its deep situation, frequently escaped the em- balmer'sknife. Otherarteries,suchasthe femorals, brachials, and common carotids, had persisted.
In some mummies examined by Ruffer the abdominal aorta was calcified in its entirety, the extreme calcification extending into the iliae arteries. Calcified plaques were also found in some of the larger branches of the aorta. The common carotid arteries frequently revealed patches of atheroma, but the most marked atheroselerotic alterations were in the arteries of the lower extremities. The common iliae arteries were not infrequently studded with calcareous plaques and in some instances the femoral arteries were converted into rigid tubes. In other mummies, however, the same arteries were near normal.
What is known as Mdnekeberg's medial calcification was also observed in some of the mummified bodies. In a histologic section of a peronieal artery, the muscular coat had been changed almost wholly by calcification. In one of Ruffer's photographic plates, a part of a calcified ulnar artery is shown. The muscular fibers had been completely replaced by calcification.
In the aorta, as in present days, the atherosclerotic process had a predilection for the points of origin of the intercostal and other arteries. The characteristics and the localization of the arterial lesions observed in Egyptian mummies leaves litle doubt that atherosclerosis in ancient times was of the same nature and degree as seen in today's postmortem examinations.
As to the prevalence of the disease, Ruffer ventured to say that the Egyptians of ancient times suffered as much as modern man from arterial lesions, identical with those found in our times. Ruffer was well qualified to make this statement having performed many autopsies on modern Egyptians, Moslems, and other people of the Middle East. In going over his material and examining the accompanying photographic plates of arteries, one can have litle doubt that what Ruffer had observed in Egyptian mummies represented arteriosclerosis as it is known today.
Although the embalming left no opportunity to examine the coronary arteries inl mummified bodies, the condition of the aorta is a good index of the decree of atheroselerosis present elsewhere. In individuals with extensive atheroselerosis of the aorta, there is almost always a considerable degree of atherosclerosis in the coronary arteries. If Ruffer's statement is correct that the Egyptians of 3,000 years ago were afflicted with arteriosclerosis as much as we are nowadays, coronary occlusion must have been common among the elderly population of the pre-Christian civilizations.
Furthermore, gangrene of the lower extremities in the aged has been recognized since the earliest records of disease. Gangrene of the extremities for centuries did not undergo critical investigation until Cruveilhier (1791- 1873) showed that it was caused by atherosclerotic arteries, associated at times with a terminal thrombus.
SUMMARY
The record of a sudden death occurring in an Egyptian noble of the Sixth Dynasty (2625-2475 B.C.) is presented. Because of the prevalence of arteriosclerosis in ancient Egyptian mummies there is presumptive evidence that this incident might represent sudden death due to atheroselerotic occlusion of the coronary arteries.
Cairo, Cairo Governorate, Egypt
945
B.C.E.
Cardiology in Ancient Egypt by Eugene V. Boisaubin, MD
Egyptians describe coronary ischemia: "if thou examinest a man for illness in his cardia and he has pains in his arms, and in his breast and in one side of his cardio... it is death threatening him."
The classic pattern of cardiac pain--radiation to the left arm--was so well known that the ancient Egyptians and Copts even identified the left ring finger as the "heart" finger.
Altogether, ancient Egyptians were aware of a variety of abnormal cardiac conditions, particularly of angina pectoris and sudden death, arrhythmia, aneurysm, congestive heart failure, and venous insufficiency. Numerous remedies for afflicitions of the heart are found throughout the Ebers payrus.
There were a range of them using different foods, some even including carbohydrates like dates or honey and dough, but interesting, there is another combination of "fat flesh, incense, garlic, and writing fluid".
Extensive histologic analysis of mummies began, however; well before the development of the scanning electron microscope. In 1912, Shattock' made sections of the calcified aorta of Pharaoh Merneptah; and the work of Sir Marc Armand Rufer, published posthumously in 1921, is our most valuable early source of information about vascular disease in ancient Egyptians. Ruffer was able to study a relatively large number of tissue specimens from mummies, mainly from New Kingdom (1600-1100 BC) burials, but covering a wide period of time. In a mummy of the 28th to 30th Dynasty (404-343 BC), he observed atheromas in the common carotids and calcific atheromas in the left subclavian, common iliac, and more peripheral arteries. Ruffer concluded from the state of the costal cartilage that this mummy was not that of an old person. A mummy of a man of the Greek period (ca. 300 to 30 BC), who died at not over 50 years of age, showed atheromas of the aorta and brachial arteries. Since the discoveries of Rufer, numerous other mummies, whose ages at death ranged from the 4th to the 8th decade, have shown similar vascular changes (Fig.4).
In 1931, Long described a female mummy of the 21st Dynasty (1070-945 BC), found at Deir-el- Bahari-that of the lady Teye, who died at about 50 years of age. The heart showed calcification of one mitral cusp, and thickening and calcification of the coronary arteries. The myocardium is said to have had patchy fibrosis, and the aorta "nodular arteriosclerosis." The renal capsule was thickened, many of the glomeruli were fibrosed, and the medium-sized renal vessels were sclerotic. The condition appears to be that of hypertensive arteriosclerotic disease associated with atheromatous change. In the 1960s, Sandison examined and photographed mummy arteries using modern histologic methods (Fig.5). Arteries in the mummy tissues were described as tape-like, but could be dissected easily, whereupon arteriosclerosis, atheroma with lipid depositions, reduplication of the internal elastic lamina, and medial calcification were readily visible under microscopy.
Still more recently, one of the most extensively studied Egyptian mummies has been PUMIL from the Pennsylvania University Museum(hence its initials), now on loan to the National Museum of Natural History at the Smithsonian. It is believed to be from the later Ptolemaic period, circa 170BC. The heart and portions of an atherosclerotic aorta were found in the abdominal cavity. Histologically, large and small arterioles and arteries from other organs showed areas of intimal fibrous thickening typical of sclerosis. These findings are particularly striking since the estimated age of PUM I at time of death was between 35 and 40 years.
